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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPH
All Species:
9.09
Human Site:
S454
Identified Species:
25
UniProt:
P41219
Number Species:
8
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41219
NP_006253.2
470
53651
S454
N
G
E
V
V
T
E
S
Q
K
E
Q
R
S
E
Chimpanzee
Pan troglodytes
Q5R1W8
466
53634
E448
T
L
L
I
K
T
V
E
T
R
D
G
Q
V
I
Rhesus Macaque
Macaca mulatta
XP_001108977
470
53605
S454
N
G
E
V
V
T
E
S
Q
K
E
Q
R
S
E
Dog
Lupus familis
XP_534812
469
53365
S453
D
G
E
V
V
T
E
S
Q
K
E
Q
R
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P15331
475
54249
E458
D
G
E
K
V
V
T
E
S
Q
K
E
Q
H
S
Rat
Rattus norvegicus
P21807
468
53531
E451
D
G
E
K
V
V
T
E
S
Q
K
E
Q
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02542
463
53261
R447
M
I
K
T
I
E
T
R
D
G
E
V
V
S
E
Frog
Xenopus laevis
P48676
456
51977
D438
I
K
T
I
E
T
R
D
G
E
Q
V
V
T
E
Zebra Danio
Brachydanio rerio
Q58EE9
444
51231
E426
S
I
V
V
R
T
V
E
T
R
D
G
E
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.7
99.7
97
N.A.
94.3
95.9
N.A.
N.A.
57.6
70.2
54.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.5
100
98.5
N.A.
96.4
97.4
N.A.
N.A.
76.5
83.4
72.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
20
20
N.A.
N.A.
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
53.3
53.3
N.A.
N.A.
33.3
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
0
0
0
12
12
0
23
0
0
0
12
% D
% Glu:
0
0
56
0
12
12
34
45
0
12
45
23
12
0
45
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
56
0
0
0
0
0
0
12
12
0
23
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% H
% Ile:
12
23
0
23
12
0
0
0
0
0
0
0
0
12
23
% I
% Lys:
0
12
12
23
12
0
0
0
0
34
23
0
0
0
0
% K
% Leu:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
23
12
34
34
0
0
% Q
% Arg:
0
0
0
0
12
0
12
12
0
23
0
0
34
0
0
% R
% Ser:
12
0
0
0
0
0
0
34
23
0
0
0
0
45
23
% S
% Thr:
12
0
12
12
0
67
34
0
23
0
0
0
0
12
0
% T
% Val:
0
0
12
45
56
23
23
0
0
0
0
23
23
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _